_fifty or EC₅₀ > 200 ?M were defined as no inhibition and no potency, respectively. Mitochondrial toxicity was defined as 5-fold higher potency in the assay with galactose (cytotoxicity with MT EC₅₀) than in the assay with glucose (cytotoxicity EC₅₀). Parenthesis (p, d, and c) of necrotic and degenerative change region represent proximal, distal, and collecting ducts, respectively.

IC

₅₀ or EC₅₀ > 200 ?M were defined as no inhibition and no potency, respectively. Mitochondrial toxicity was defined as 5-fold higher potency in the assay with galactose (cytotoxicity with MT EC₅₀) than in the assay with glucose (cytotoxicity EC₅₀).

IC

₅₀ or EC₅₀ > 200 ?M were defined as no inhibition and no potency, respectively. Mitochondrial toxicity was defined as 5-fold higher potency in the assay with galactose (cytotoxicity with MT EC₅₀) than in the assay with glucose (cytotoxicity EC₅₀). Leer más